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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE3B All Species: 26.67
Human Site: T483 Identified Species: 45.13
UniProt: Q7Z3V4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z3V4 NP_569733.2 1068 123070 T483 Q I R L Q I L T G L T Y L D D
Chimpanzee Pan troglodytes XP_509354 1068 122921 T483 Q I R L Q I L T G L T Y L D D
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_543437 1068 123121 T483 Q I R L Q I L T G L T Y L D D
Cat Felis silvestris
Mouse Mus musculus Q9ES34 1070 122743 T485 Q I R L Q I L T G L T Y L D D
Rat Rattus norvegicus NP_001137366 1070 122598 T485 Q I R L Q I L T G L T Y L D D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423951 837 96057 Y318 C L L G N L V Y L G S L N D K
Frog Xenopus laevis Q6DCL5 944 106566 C422 R D S S N I A C I L L K Q S P
Zebra Danio Brachydanio rerio A9JRZ0 765 87445 H246 R N Y M S R T H L H T P P D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVI3 1007 114856 I461 Q Q Q Q Q N R I L L D V D H R
Honey Bee Apis mellifera XP_392283 1063 121439 T479 Q M K M E I L T G L C Y Q D K
Nematode Worm Caenorhab. elegans NP_499392 1066 120863 S471 H M K G E I I S G L C R D D Q
Sea Urchin Strong. purpuratus XP_786887 582 66877 E63 I A I L D D G E F Y D Q Q I P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWB8 1029 117643 L470 R T E L V A V L W N Y M K R C
Baker's Yeast Sacchar. cerevisiae P53119 910 105547 Y391 K D F T F R Q Y W E L P K S E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.2 N.A. 96.5 N.A. 92.1 91.8 N.A. N.A. 68.6 20.8 22.8 N.A. 20.4 51.5 37.6 37.1
Protein Similarity: 100 98.9 N.A. 98.5 N.A. 96 96.1 N.A. N.A. 74 40.1 38.4 N.A. 37.1 69.1 58.4 44.9
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 6.6 13.3 13.3 N.A. 20 53.3 26.6 6.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 33.3 20 26.6 N.A. 26.6 80 60 6.6
Percent
Protein Identity: N.A. N.A. N.A. 28.7 25.1 N.A.
Protein Similarity: N.A. N.A. N.A. 48.7 42 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 8 8 0 0 0 0 0 0 0 0 % A
% Cys: 8 0 0 0 0 0 0 8 0 0 15 0 0 0 8 % C
% Asp: 0 15 0 0 8 8 0 0 0 0 15 0 15 65 36 % D
% Glu: 0 0 8 0 15 0 0 8 0 8 0 0 0 0 8 % E
% Phe: 0 0 8 0 8 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 0 0 0 15 0 0 8 0 50 8 0 0 0 0 0 % G
% His: 8 0 0 0 0 0 0 8 0 8 0 0 0 8 0 % H
% Ile: 8 36 8 0 0 58 8 8 8 0 0 0 0 8 0 % I
% Lys: 8 0 15 0 0 0 0 0 0 0 0 8 15 0 15 % K
% Leu: 0 8 8 50 0 8 43 8 22 65 15 8 36 0 8 % L
% Met: 0 15 0 15 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 8 0 0 15 8 0 0 0 8 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 15 8 0 15 % P
% Gln: 50 8 8 8 43 0 8 0 0 0 0 8 22 0 8 % Q
% Arg: 22 0 36 0 0 15 8 0 0 0 0 8 0 8 8 % R
% Ser: 0 0 8 8 8 0 0 8 0 0 8 0 0 15 0 % S
% Thr: 0 8 0 8 0 0 8 43 0 0 43 0 0 0 0 % T
% Val: 0 0 0 0 8 0 15 0 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 15 0 8 8 43 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _